CLIPPERS: A Rare Neurological Disorder

Introduction

Chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS) is a rare neurological disorder that primarily affects young women. It can cause a wide range of symptoms, including fatigue, headache, dizziness, muscle weakness, and cognitive impairment.

What is CLIPPERS?

CLIPPERS is an inflammatory condition that affects the brain and spinal cord. It is characterized by the presence of chronic lymphocytic inflammation in the perivascular spaces (the areas around blood vessels) of the pons and cerebellum, two regions of the brain that are involved in coordination, movement, and other functions.

Symptoms of CLIPPERS

The symptoms of CLIPPERS can vary depending on the severity of the inflammation and the areas of the brain and spinal cord affected. Common symptoms include:

• Fatigue
• Headache
• Dizziness
• Muscle weakness
• Cognitive impairment
• Speech problems
• Balance problems
• Eye movement problems
• Numbness or tingling in the hands and feet